Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50223481'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50223481 (6-(3-aminopropyl)-9-(1-methyl-1H-pyrazol-4-yl)benz...) Show SMILES Cn1cc(cn1)-c1ccc2c(CCCN)cc3cc[nH]c(=O)c3c2c1 Show InChI InChI=1S/C20H20N4O/c1-24-12-16(11-23-24)13-4-5-17-14(3-2-7-21)9-15-6-8-22-20(25)19(15)18(17)10-13/h4-6,8-12H,2-3,7,21H2,1H3,(H,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Chk1 expressed in baculovirus by time-resolved fluorescence assay				Bioorg Med Chem Lett 17: 6280-5 (2007) Article DOI: 10.1016/j.bmcl.2007.09.007 BindingDB Entry DOI: 10.7270/Q2W958ZJ
					More data for this Ligand-Target Pair				3D Structure (docked)