Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50243666'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50243666 ((+/-)-1-(5-(3-(2-(diethylamino)ethoxy)phenyl)-3-(p...) Show SMILES CCN(CC)CCOc1cccc(c1)-c1cc(C(=O)NC2CCCNC2)c(NC(N)=O)s1 Show InChI InChI=1S/C23H33N5O3S/c1-3-28(4-2)11-12-31-18-9-5-7-16(13-18)20-14-19(22(32-20)27-23(24)30)21(29)26-17-8-6-10-25-15-17/h5,7,9,13-14,17,25H,3-4,6,8,10-12,15H2,1-2H3,(H,26,29)(H3,24,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of Chk1				Bioorg Med Chem Lett 18: 4242-8 (2008) Article DOI: 10.1016/j.bmcl.2008.05.016 BindingDB Entry DOI: 10.7270/Q2J102Z9
					More data for this Ligand-Target Pair