Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk2' and Ligand = 'BDBM50163257'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50163257 (2-[4-(3-Diethylcarbamoyl-phenoxy)-phenyl]-1H-benzo...) Show SMILES CCN(CC)C(=O)c1cccc(Oc2ccc(cc2)-c2nc3ccc(cc3[nH]2)C(N)=O)c1 Show InChI InChI=1S/C25H24N4O3/c1-3-29(4-2)25(31)18-6-5-7-20(14-18)32-19-11-8-16(9-12-19)24-27-21-13-10-17(23(26)30)15-22(21)28-24/h5-15H,3-4H2,1-2H3,(H2,26,30)(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of recombinant human Chk2 kinase				J Med Chem 48: 1873-85 (2005) Article DOI: 10.1021/jm0495935 BindingDB Entry DOI: 10.7270/Q2FQ9W4V
					More data for this Ligand-Target Pair