Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase MARK2' and Ligand = 'BDBM247044'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase MARK2 (Homo sapiens (Human))	BDBM247044 (3-((1R,3aR,6S, 7R,7aS)-7 -((E)- 2- (2'-cyano-[...) Show SMILES C[C@H]1OC(=O)[C@]2(CCC(N)=O)CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3cccnc3C#N)[C@H]12 |r| Show InChI InChI=1S/C26H26F2N4O3/c1-15-19(8-7-18-6-5-17(13-32-18)20-4-3-11-31-21(20)12-29)23-16(2)35-24(34)25(23,10-9-22(30)33)14-26(15,27)28/h3-8,11,13,15-16,19,23H,9-10,14H2,1-2H3,(H2,30,33)/b8-7+/t15-,16+,19-,23-,25+/m0/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.34	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description This assay measures the potency of the inventive compounds as PAR-1 receptor antagonists.Frozen HEK 293 Cells were plated in 384-well PDL coated plat...				US Patent US9701669 (2017) BindingDB Entry DOI: 10.7270/Q2PC34DS
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