Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase NLK' and Ligand = 'BDBM6511'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase NLK (Homo sapiens (Human))	BDBM6511 (4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...) Show SMILES COc1cc(Nc2ccnc3cc(OC)c(OC)cc23)cc(OC)c1OC Show InChI InChI=1S/C20H22N2O5/c1-23-16-10-13-14(6-7-21-15(13)11-17(16)24-2)22-12-8-18(25-3)20(27-5)19(9-12)26-4/h6-11H,1-5H3,(H,21,22)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to wild-type human full length NLK expressed in bacterial expression system by Kinomescan method				Citation and Details Article DOI: 10.1016/j.bmcl.2019.05.025 BindingDB Entry DOI: 10.7270/Q21J9FC5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase NLK (Homo sapiens (Human))	BDBM6511 (4-Anilinoquinoline deriv. 8 | 6,7-dimethoxy-N-(3,4...) Show SMILES COc1cc(Nc2ccnc3cc(OC)c(OC)cc23)cc(OC)c1OC Show InChI InChI=1S/C20H22N2O5/c1-23-16-10-13-14(6-7-21-15(13)11-17(16)24-2)22-12-8-18(25-3)20(27-5)19(9-12)26-4/h6-11H,1-5H3,(H,21,22)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Binding affinity to biotinylated full length human NLK expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET ba...				J Med Chem 62: 2830-2836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01213 BindingDB Entry DOI: 10.7270/Q28919C7
					More data for this Ligand-Target Pair