Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 4' and Ligand = 'BDBM101476'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM101476 (US8524710, 53 | US8530652, 3 | US8530652, 47) Show SMILES CN1CCN([C@@H](Cc2ccccc2)C1)C(=O)N1Cc2c(Nc3nc(Cl)nc4ccsc34)[nH]nc2C1(C)C |r| Show InChI InChI=1S/C26H29ClN8OS/c1-26(2)21-18(22(32-31-21)29-23-20-19(9-12-37-20)28-24(27)30-23)15-35(26)25(36)34-11-10-33(3)14-17(34)13-16-7-5-4-6-8-16/h4-9,12,17H,10-11,13-15H2,1-3H3,(H2,28,29,30,31,32)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	11	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent					Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...				US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4
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