Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 4' and Ligand = 'BDBM101488'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM101488 (US8524710, 66 | US8530652, 15 | US8530652, 59) Show SMILES CN(C)c1nc(Cl)nc(Nc2[nH]nc3c2CN(C(=O)NC2CC2c2ccccc2)C3(C)C)n1 Show InChI InChI=1S/C22H26ClN9O/c1-22(2)16-14(17(30-29-16)25-19-26-18(23)27-20(28-19)31(3)4)11-32(22)21(33)24-15-10-13(15)12-8-6-5-7-9-12/h5-9,13,15H,10-11H2,1-4H3,(H,24,33)(H2,25,26,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	90	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent					Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...				US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4
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