Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 4' and Ligand = 'BDBM101496'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM101496 (US8524710, 74 | US8530652, 23 | US8530652, 67) Show SMILES CN(C)c1nc(Nc2[nH]nc3c2CN(C(=O)NC2C[C@@H]2c2ccccc2)C3(C)C)nc(n1)N1CCC[C@H]1CO |r| Show InChI InChI=1S/C27H36N10O2/c1-27(2)21-19(14-37(27)26(39)28-20-13-18(20)16-9-6-5-7-10-16)22(34-33-21)29-23-30-24(35(3)4)32-25(31-23)36-12-8-11-17(36)15-38/h5-7,9-10,17-18,20,38H,8,11-15H2,1-4H3,(H,28,39)(H2,29,30,31,32,33,34)/t17-,18+,20?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	140	n/a	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent					Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...				US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4
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