Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 4' and Ligand = 'BDBM101498'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM101498 (US8524710, 76 | US8530652, 25 | US8530652, 69) Show SMILES CC1(C)N(Cc2c(Nc3cc(ccn3)C(F)(F)F)n[nH]c12)C(=O)NC1C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C23H23F3N6O/c1-22(2)19-16(20(31-30-19)29-18-10-14(8-9-27-18)23(24,25)26)12-32(22)21(33)28-17-11-15(17)13-6-4-3-5-7-13/h3-10,15,17H,11-12H2,1-2H3,(H,28,33)(H2,27,29,30,31)/t15-,17?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent					Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...				US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4
					More data for this Ligand-Target Pair