Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PAK 4' and Ligand = 'BDBM101511'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM101511 (US8524699, 7 | US8530652, 38 | US8530652, 83) Show SMILES CN(C)c1cc(Nc2[nH]nc3c2CN(C(=O)N[C@@H]2C[C@H]2c2ccccc2)C3(C)C)nc(C)n1 |r| Show InChI InChI=1S/C24H30N8O/c1-14-25-19(12-20(26-14)31(4)5)28-22-17-13-32(24(2,3)21(17)29-30-22)23(33)27-18-11-16(18)15-9-7-6-8-10-15/h6-10,12,16,18H,11,13H2,1-5H3,(H,27,33)(H2,25,26,28,29,30)/t16-,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	96	n/a	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a
Agouron Pharmaceuticals, Inc.; Pfizer Inc. US Patent					Assay Description The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...				US Patent US8530652 (2013) BindingDB Entry DOI: 10.7270/Q2F18XC4
					More data for this Ligand-Target Pair