Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase PLK1' and Ligand = 'BDBM50308197'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308197 (2-(4-Hydroxyanilino)-5,7-dihydro-6H-pyrido[4,3-b]p...) Show SMILES Oc1ccc(Nc2ncc3CC(=O)Nc4ccncc4-c3n2)cc1 Show InChI InChI=1S/C17H13N5O2/c23-12-3-1-11(2-4-12)20-17-19-8-10-7-15(24)21-14-5-6-18-9-13(14)16(10)22-17/h1-6,8-9,23H,7H2,(H,21,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair