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Target
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Compile Data Set for Download or QSAR
Found
4
hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase RIO2' and Ligand = 'BDBM50550127'
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
Serine/threonine-protein kinase RIO2
(Homo sapiens (Human))
BDBM50550127
(CHEMBL4781866)
Show SMILES
Cc1ccnc(NC(=O)Cc2ccc3ccccc3c2)c1
Show InChI
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
1.46E+4
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Citation and Details
Article DOI:
10.1021/acs.jmedchem.2c00271
BindingDB Entry DOI:
10.7270/Q2930Z8M
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase RIO2
(Homo sapiens (Human))
BDBM50550127
(CHEMBL4781866)
Show SMILES
Cc1ccnc(NC(=O)Cc2ccc3ccccc3c2)c1
Show InChI
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
1.46E+4
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...
Citation and Details
Article DOI:
10.1039/d0md00292e
BindingDB Entry DOI:
10.7270/Q2251NSH
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase RIO2
(Homo sapiens (Human))
BDBM50550127
(CHEMBL4781866)
Show SMILES
Cc1ccnc(NC(=O)Cc2ccc3ccccc3c2)c1
Show InChI
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
n/a
150
n/a
n/a
n/a
n/a
n/a
TBA
Citation and Details
Article DOI:
10.1021/acs.jmedchem.2c00271
BindingDB Entry DOI:
10.7270/Q2930Z8M
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase RIO2
(Homo sapiens (Human))
BDBM50550127
(CHEMBL4781866)
Show SMILES
Cc1ccnc(NC(=O)Cc2ccc3ccccc3c2)c1
Show InChI
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/a
n/a
n/a
140
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Binding affinity to RIOK2 (unknown origin)
Citation and Details
Article DOI:
10.1039/d0md00292e
BindingDB Entry DOI:
10.7270/Q2251NSH
More data for this
Ligand-Target Pair
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