Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM144129'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM144129 (US8969335, A66) Show SMILES N#Cc1cc(ccc1OC1CCOCC1)-c1ccnc(Nc2ncc(cn2)C2CCNCC2)c1 Show InChI InChI=1S/C26H28N6O2/c27-15-21-13-19(1-2-24(21)34-23-6-11-33-12-7-23)20-5-10-29-25(14-20)32-26-30-16-22(17-31-26)18-3-8-28-9-4-18/h1-2,5,10,13-14,16-18,23,28H,3-4,6-9,11-12H2,(H,29,30,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	7.5	30
MERCK PATENT GmbH US Patent					Assay Description The kinase assay is performed as 384-well flashplate assay (for example for Topcount measurement).0.6 nM TANK binding kinase (TBK1), 800 nM biotinyla...				US Patent US8969335 (2015) BindingDB Entry DOI: 10.7270/Q25X27NN
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