Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM144155'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM144155 (US8969335, A92) Show SMILES N#Cc1cc(ccc1OC1CCOCC1)-c1ccnc(Nc2cncc(n2)C2=CCCCO2)c1 |t:30| Show InChI InChI=1S/C26H25N5O3/c27-15-20-13-18(4-5-23(20)34-21-7-11-32-12-8-21)19-6-9-29-25(14-19)31-26-17-28-16-22(30-26)24-3-1-2-10-33-24/h3-6,9,13-14,16-17,21H,1-2,7-8,10-12H2,(H,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	850	n/a	n/a	n/a	n/a	7.5	30
MERCK PATENT GmbH US Patent					Assay Description The kinase assay is performed as 384-well flashplate assay (for example for Topcount measurement).0.6 nM TANK binding kinase (TBK1), 800 nM biotinyla...				US Patent US8969335 (2015) BindingDB Entry DOI: 10.7270/Q25X27NN
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