Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM144176'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM144176 (US8969335, A112) Show SMILES [C-]#[N+]c1cc(ccc1OCC1CCC1)-c1ccnc(Nc2ccn(n2)C2CCNCC2)c1 Show InChI InChI=1S/C25H28N6O/c1-26-22-15-19(5-6-23(22)32-17-18-3-2-4-18)20-7-13-28-25(16-20)29-24-10-14-31(30-24)21-8-11-27-12-9-21/h5-7,10,13-16,18,21,27H,2-4,8-9,11-12,17H2,(H,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	7.5	30
MERCK PATENT GmbH US Patent					Assay Description The kinase assay is performed as 384-well flashplate assay (for example for Topcount measurement).0.6 nM TANK binding kinase (TBK1), 800 nM biotinyla...				US Patent US8969335 (2015) BindingDB Entry DOI: 10.7270/Q25X27NN
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