Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM144181'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM144181 (US8969335, A117) Show SMILES CC(=O)N1CCC(COc2ccc(cc2[N+]#[C-])-c2ccnc(Nc3ccc(cn3)N3CCOCC3)c2)CC1 Show InChI InChI=1S/C29H32N6O3/c1-21(36)34-11-8-22(9-12-34)20-38-27-5-3-23(17-26(27)30-2)24-7-10-31-29(18-24)33-28-6-4-25(19-32-28)35-13-15-37-16-14-35/h3-7,10,17-19,22H,8-9,11-16,20H2,1H3,(H,31,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	810	n/a	n/a	n/a	n/a	7.5	30
MERCK PATENT GmbH US Patent					Assay Description The kinase assay is performed as 384-well flashplate assay (for example for Topcount measurement).0.6 nM TANK binding kinase (TBK1), 800 nM biotinyla...				US Patent US8969335 (2015) BindingDB Entry DOI: 10.7270/Q25X27NN
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