Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM144186'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM144186 (US8969335, A9) Show SMILES N#Cc1cc(ccc1OC1CCOCC1)-c1ccnc(Nc2ccc(cn2)-c2cn[nH]c2)c1 Show InChI InChI=1S/C25H22N6O2/c26-13-20-11-17(1-3-23(20)33-22-6-9-32-10-7-22)18-5-8-27-25(12-18)31-24-4-2-19(14-28-24)21-15-29-30-16-21/h1-5,8,11-12,14-16,22H,6-7,9-10H2,(H,29,30)(H,27,28,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	7.5	30
MERCK PATENT GmbH US Patent					Assay Description The kinase assay is performed as 384-well flashplate assay (for example for Topcount measurement).0.6 nM TANK binding kinase (TBK1), 800 nM biotinyla...				US Patent US8969335 (2015) BindingDB Entry DOI: 10.7270/Q25X27NN
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