Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM357888'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM357888 (Ethyl 2-amino-7-(4,4-dimethylcyclohexyl)-5-oxo-5H-...) Show SMILES CCOC(=O)c1cc2c(nc1N)oc1ccc(cc1c2=O)C1CCC(C)(C)CC1 Show InChI InChI=1S/C23H26N2O4/c1-4-28-22(27)17-12-16-19(26)15-11-14(13-7-9-23(2,3)10-8-13)5-6-18(15)29-21(16)25-20(17)24/h5-6,11-13H,4,7-10H2,1-3H3,(H2,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Kinase assays are commonly used for determining the ability of a small molecule to inhibit enzyme activity. By measuring the degree of phosphorylatio...				US Patent US10214536 (2019) BindingDB Entry DOI: 10.7270/Q2N87D2S
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