Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM50379360'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM50379360 (CHEMBL2011937) Show SMILES COc1ccc(cc1)-c1nc2ncc(Br)c(NCCCNC(=O)c3ccccc3)c2[nH]1 Show InChI InChI=1S/C23H22BrN5O2/c1-31-17-10-8-15(9-11-17)21-28-20-19(18(24)14-27-22(20)29-21)25-12-5-13-26-23(30)16-6-3-2-4-7-16/h2-4,6-11,14H,5,12-13H2,1H3,(H,26,30)(H2,25,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of recombinant TBK1 using 5FAM-AhxKRRAL(ps)VASLPGL as substrate by microfluidic mobility shift assay				Bioorg Med Chem Lett 22: 2063-9 (2012) Article DOI: 10.1016/j.bmcl.2012.01.018 BindingDB Entry DOI: 10.7270/Q2WS8V74
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM50379360 (CHEMBL2011937) Show SMILES COc1ccc(cc1)-c1nc2ncc(Br)c(NCCCNC(=O)c3ccccc3)c2[nH]1 Show InChI InChI=1S/C23H22BrN5O2/c1-31-17-10-8-15(9-11-17)21-28-20-19(18(24)14-27-22(20)29-21)25-12-5-13-26-23(30)16-6-3-2-4-7-16/h2-4,6-11,14H,5,12-13H2,1H3,(H,26,30)(H2,25,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of TBK1-mediated NFkappaB activation expressed in ds-RNA activated HEK293 cells coexpressing TLR3 after 4.5 hrs by luciferase reporter gen...				Bioorg Med Chem Lett 22: 2063-9 (2012) Article DOI: 10.1016/j.bmcl.2012.01.018 BindingDB Entry DOI: 10.7270/Q2WS8V74
					More data for this Ligand-Target Pair