Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TBK1' and Ligand = 'BDBM50401941'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM50401941 (CHEMBL2207220) Show SMILES Fc1cccc(Nc2ncc(Br)c(NCCCNC(=O)c3ccc(cc3)C(F)(F)F)n2)c1 Show InChI InChI=1S/C21H18BrF4N5O/c22-17-12-29-20(30-16-4-1-3-15(23)11-16)31-18(17)27-9-2-10-28-19(32)13-5-7-14(8-6-13)21(24,25)26/h1,3-8,11-12H,2,9-10H2,(H,28,32)(H2,27,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
MRC Technology Curated by ChEMBL					Assay Description Inhibition of TBK1 by radiometry				Bioorg Med Chem Lett 22: 7169-73 (2012) Article DOI: 10.1016/j.bmcl.2012.09.063 BindingDB Entry DOI: 10.7270/Q2TT4S45
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