Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM111750'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM111750 (US8618111, H-23) Show SMILES CCc1ncnc(N2CCN(CC2)c2cccnc2)c1C#Cc1ccc(N)nc1 Show InChI InChI=1S/C22H23N7/c1-2-20-19(7-5-17-6-8-21(23)25-14-17)22(27-16-26-20)29-12-10-28(11-13-29)18-4-3-9-24-15-18/h3-4,6,8-9,14-16H,2,10-13H2,1H3,(H2,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.5	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The mTOR kinase TR-FRET assay utilizes a physiologically relevant protein substrate for mTOR (4E-BP1, labeled with an acceptor fluorophore (Green Flu...				US Patent US8618111 (2013) BindingDB Entry DOI: 10.7270/Q2FX7838
					More data for this Ligand-Target Pair