Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM122462'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM122462 (US8729074, 22) Show SMILES CN(C)S(=O)(=O)Nc1cc(cnc1Cl)-c1cnc2cc(ccn12)-c1cccnc1 Show InChI InChI=1S/C19H17ClN6O2S/c1-25(2)29(27,28)24-16-8-15(11-23-19(16)20)17-12-22-18-9-13(5-7-26(17)18)14-4-3-6-21-10-14/h3-12,24H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description The Invitrogen (Carlsbad, Calif.) mammalian target of rapamycin (mTOR) Lanthascreen assay can be used to quantitate mTOR kinase activity in an in vit...				US Patent US8729074 (2014) BindingDB Entry DOI: 10.7270/Q2RJ4H4G
					More data for this Ligand-Target Pair