Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM178283'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM178283 (US9120812, 68) Show SMILES CN1CC(C)(C)Oc2nc(nc(-c3ccc(NC(=O)Nc4ccncc4)cc3)c2C1=O)N1C2CCC1COC2 Show InChI InChI=1S/C28H31N7O4/c1-28(2)16-34(3)25(36)22-23(32-26(33-24(22)39-28)35-20-8-9-21(35)15-38-14-20)17-4-6-18(7-5-17)30-27(37)31-19-10-12-29-13-11-19/h4-7,10-13,20-21H,8-9,14-16H2,1-3H3,(H2,29,30,31,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.5	25
Sanofi US Patent					Assay Description The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...				US Patent US9120812 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M2D
					More data for this Ligand-Target Pair