Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM178299'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM178299 (US9120812, 84) Show SMILES CCN1CC(C)(C)Oc2nc(nc(-c3ccc(NC(=O)Nc4ccccn4)cc3F)c2C1=O)N1CC2CCC(C1)O2 Show InChI InChI=1S/C29H32FN7O4/c1-4-36-16-29(2,3)41-25-23(26(36)38)24(34-27(35-25)37-14-18-9-10-19(15-37)40-18)20-11-8-17(13-21(20)30)32-28(39)33-22-7-5-6-12-31-22/h5-8,11-13,18-19H,4,9-10,14-16H2,1-3H3,(H2,31,32,33,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	7.5	25
Sanofi US Patent					Assay Description The test detects the phosphorylation of the substrate GFP-4EBP1 using a terbium-labelled antibody that is specific for the phospho-Thr46 epitope. Bin...				US Patent US9120812 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M2D
					More data for this Ligand-Target Pair