Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase mTOR (Homo sapiens (Human)) | BDBM21034 ((1R,3R,5S,6S,18S)-6-hydroxy-18-(methoxymethyl)-1,5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 193 | n/a | n/a | n/a | n/a | 7.4 | 30 |
Wyeth Research | Assay Description The enzyme was assayed in DELFIA format using purified FLAG-TOR in kinase buffer containing ATP and His6-S6K in the presence of inhibitor compounds. ... | J Med Chem 51: 1319-23 (2008) Article DOI: 10.1021/jm7012858 BindingDB Entry DOI: 10.7270/Q2NP22QD | |||||||||||
More data for this Ligand-Target Pair |