Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM227484'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM227484 (US9334271, 5) Show SMILES C[C@H]1COCCN1c1nc(N2CCOC[C@H]2C)c2nc([nH]c2n1)-c1cc(F)cc2[nH]ccc12 |r| Show InChI InChI=1S/C23H24FN7O2/c1-13-11-32-7-5-30(13)22-19-21(28-23(29-22)31-6-8-33-12-14(31)2)27-20(26-19)17-9-15(24)10-18-16(17)3-4-25-18/h3-4,9-10,13-14H,5-8,11-12H2,1-2H3/b20-17-/t13-,14+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	7.5	25
Novarits AG US Patent					Assay Description 1. 8-point serial dilutions of compounds (10 mM stock) are performed in 90% DMSO in a 384-well "masterplate" and 50 nL is transferred onto 384-well a...				US Patent US9334271 (2016) BindingDB Entry DOI: 10.7270/Q2P55MCT
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