Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM227488'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM227488 (US9334271, 9) Show SMILES C1CN(CCO1)c1nc(N2CCOCC2)c2nc([nH]c2n1)-c1ccccn1 Show InChI InChI=1S/C18H21N7O2/c1-2-4-19-13(3-1)15-20-14-16(21-15)22-18(25-7-11-27-12-8-25)23-17(14)24-5-9-26-10-6-24/h1-4H,5-12H2,(H,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	860	n/a	n/a	n/a	n/a	7.5	25
Novarits AG US Patent					Assay Description 1. 8-point serial dilutions of compounds (10 mM stock) are performed in 90% DMSO in a 384-well "masterplate" and 50 nL is transferred onto 384-well a...				US Patent US9334271 (2016) BindingDB Entry DOI: 10.7270/Q2P55MCT
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