Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM346183'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM346183 (US10202371, Example 13) Show SMILES Nc1ncc(-c2cc(nc(n2)N2CCOCC2)N2[C@@H](CO)[C@@H](OC2=O)c2ccc(OCCO)cc2)c(n1)C(F)(F)F |r| Show InChI InChI=1S/C25H26F3N7O6/c26-25(27,28)21-16(12-30-22(29)33-21)17-11-19(32-23(31-17)34-5-8-39-9-6-34)35-18(13-37)20(41-24(35)38)14-1-3-15(4-2-14)40-10-7-36/h1-4,11-12,18,20,36-37H,5-10,13H2,(H2,29,30,33)/t18-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description TR-FRET assays for protein kinases uses a long-lifetime lanthanide Terbium or Europium chelates as the donor species which overcome interference by c...				US Patent US10202371 (2019) BindingDB Entry DOI: 10.7270/Q2KD2123
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