Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50039850'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50039850 (CHEMBL3357873) Show SMILES COc1ccc(Nc2ncc(cc2-c2nc(C)nc(N)n2)C(C)(C)O)cn1 Show InChI InChI=1S/C18H21N7O2/c1-10-22-16(25-17(19)23-10)13-7-11(18(2,3)26)8-21-15(13)24-12-5-6-14(27-4)20-9-12/h5-9,26H,1-4H3,(H,21,24)(H2,19,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminally GST-tagged mTOR (1360 to 2549 aa) (unknown origin) assessed as inhibition of 27BP1 phosphorylation after 90 mi...				Bioorg Med Chem Lett 24: 5630-4 (2014) Article DOI: 10.1016/j.bmcl.2014.10.085 BindingDB Entry DOI: 10.7270/Q2GQ70CS
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