Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50119608'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50119608 (CHEMBL3618232) Show SMILES CCOc1ccc(Nc2nc3ccccn3c2-c2nc(C)nc(N)n2)cn1 Show InChI InChI=1S/C18H18N8O/c1-3-27-14-8-7-12(10-20-14)23-17-15(16-21-11(2)22-18(19)25-16)26-9-5-4-6-13(26)24-17/h4-10,23H,3H2,1-2H3,(H2,19,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assay				Bioorg Med Chem Lett 25: 4136-42 (2015) Article DOI: 10.1016/j.bmcl.2015.08.016 BindingDB Entry DOI: 10.7270/Q2R49SKC
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