Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50119613'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50119613 (CHEMBL3618237) Show SMILES Cc1nc(N)nc(n1)-c1c(Nc2cccc3[nH]ncc23)nc2ccccn12 Show InChI InChI=1S/C18H15N9/c1-10-21-16(25-18(19)22-10)15-17(24-14-7-2-3-8-27(14)15)23-12-5-4-6-13-11(12)9-20-26-13/h2-9,23H,1H3,(H,20,26)(H2,19,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assay				Bioorg Med Chem Lett 25: 4136-42 (2015) Article DOI: 10.1016/j.bmcl.2015.08.016 BindingDB Entry DOI: 10.7270/Q2R49SKC
					More data for this Ligand-Target Pair