Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50316291'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50316291 (CHEMBL1095281 | N-Methyl-N-[4-(4-morpholin-4-yl-1-...) Show SMILES CN(C(C)=O)c1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(-c3ccccc3)c2n1 Show InChI InChI=1S/C24H24N6O2/c1-17(31)28(2)19-10-8-18(9-11-19)22-26-23(29-12-14-32-15-13-29)21-16-25-30(24(21)27-22)20-6-4-3-5-7-20/h3-11,16H,12-15H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cells				J Med Chem 52: 8010-24 (2009) Article DOI: 10.1021/jm9013828 BindingDB Entry DOI: 10.7270/Q28W3DGF
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