Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50333022'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50333022 (3-(Cyclopropylethynyl)-1H-indazole | CHEMBL1631897) Show SMILES C1CC1C#Cc1n[nH]c2ccccc12 Show InChI InChI=1S/C12H10N2/c1-2-4-11-10(3-1)12(14-13-11)8-7-9-5-6-9/h1-4,9H,5-6H2,(H,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assay				J Med Chem 53: 8368-8375 (2010) Article DOI: 10.1021/jm100825h BindingDB Entry DOI: 10.7270/Q2NP24PS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50333022 (3-(Cyclopropylethynyl)-1H-indazole | CHEMBL1631897) Show SMILES C1CC1C#Cc1n[nH]c2ccccc12 Show InChI InChI=1S/C12H10N2/c1-2-4-11-10(3-1)12(14-13-11)8-7-9-5-6-9/h1-4,9H,5-6H2,(H,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of mTOR by LanthaScreen Eu kinase binding assay				J Med Chem 53: 8368-8375 (2010) Article DOI: 10.1021/jm100825h BindingDB Entry DOI: 10.7270/Q2NP24PS
					More data for this Ligand-Target Pair