Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50333028'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50333028 (3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...) Show SMILES c1ccc2c(n[nH]c2c1)C#Cc1cccnc1 Show InChI InChI=1S/C14H9N3/c1-2-6-13-12(5-1)14(17-16-13)8-7-11-4-3-9-15-10-11/h1-6,9-10H,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assay				J Med Chem 53: 8368-8375 (2010) Article DOI: 10.1021/jm100825h BindingDB Entry DOI: 10.7270/Q2NP24PS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50333028 (3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...) Show SMILES c1ccc2c(n[nH]c2c1)C#Cc1cccnc1 Show InChI InChI=1S/C14H9N3/c1-2-6-13-12(5-1)14(17-16-13)8-7-11-4-3-9-15-10-11/h1-6,9-10H,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of mTOR by LanthaScreen Eu kinase binding assay				J Med Chem 53: 8368-8375 (2010) Article DOI: 10.1021/jm100825h BindingDB Entry DOI: 10.7270/Q2NP24PS
					More data for this Ligand-Target Pair