Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50333031'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50333031 (4-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163188...) Show SMILES Nc1ccc(cc1)C#Cc1n[nH]c2ccccc12 Show InChI InChI=1S/C15H11N3/c16-12-8-5-11(6-9-12)7-10-15-13-3-1-2-4-14(13)17-18-15/h1-6,8-9H,16H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of mTOR by LanthaScreen Eu kinase binding assay				J Med Chem 53: 8368-8375 (2010) Article DOI: 10.1021/jm100825h BindingDB Entry DOI: 10.7270/Q2NP24PS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50333031 (4-((1H-Indazol-3-yl)ethynyl)aniline | CHEMBL163188...) Show SMILES Nc1ccc(cc1)C#Cc1n[nH]c2ccccc12 Show InChI InChI=1S/C15H11N3/c16-12-8-5-11(6-9-12)7-10-15-13-3-1-2-4-14(13)17-18-15/h1-6,8-9H,16H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assay				J Med Chem 53: 8368-8375 (2010) Article DOI: 10.1021/jm100825h BindingDB Entry DOI: 10.7270/Q2NP24PS
					More data for this Ligand-Target Pair