Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50346964'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Mus musculus (Mouse))	BDBM50346964 (CHEMBL1795878) Show SMILES OCc1ccc(cc1)-c1ccc(cc1C(F)(F)F)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1cnc2ccccc2c1 Show InChI InChI=1S/C35H22F3N3O2/c36-35(37,38)30-17-27(11-12-28(30)22-7-5-21(20-42)6-8-22)41-33(43)14-10-25-18-40-32-13-9-23(16-29(32)34(25)41)26-15-24-3-1-2-4-31(24)39-19-26/h1-19,42H,20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Dana Farber Cancer Institute Curated by ChEMBL					Assay Description Inhibition of mTOR-dependent S6K phosphorylation at T389 residue in MEF cells				Bioorg Med Chem Lett 21: 4036-40 (2011) Article DOI: 10.1016/j.bmcl.2011.04.129 BindingDB Entry DOI: 10.7270/Q2Z60PD1
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