Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50396295'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50396295 (CHEMBL2172478) Show SMILES CC(C)n1cc(cn1)-c1ccc2nc(Nc3ccn(C)n3)c(-c3cc(NC(C)=O)nc(C)n3)n2c1 Show InChI InChI=1S/C24H26N10O/c1-14(2)34-13-18(11-25-34)17-6-7-22-30-24(29-20-8-9-32(5)31-20)23(33(22)12-17)19-10-21(28-16(4)35)27-15(3)26-19/h6-14H,1-5H3,(H,29,31)(H,26,27,28,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of mTOR by LanthaScreen assay				Bioorg Med Chem Lett 22: 4967-74 (2012) Article DOI: 10.1016/j.bmcl.2012.06.033 BindingDB Entry DOI: 10.7270/Q2BK1DHN
					More data for this Ligand-Target Pair