Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50396300'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50396300 (CHEMBL2172487) Show SMILES CC(=O)Nc1cccc(c1)-c1ccc2nc(Nc3ccn[nH]3)c(-c3nc(C)nc(N)n3)n2c1 Show InChI InChI=1S/C22H20N10O/c1-12-25-20(30-22(23)26-12)19-21(28-17-8-9-24-31-17)29-18-7-6-15(11-32(18)19)14-4-3-5-16(10-14)27-13(2)33/h3-11H,1-2H3,(H,27,33)(H2,24,28,31)(H2,23,25,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of mTOR by LanthaScreen assay				Bioorg Med Chem Lett 22: 4967-74 (2012) Article DOI: 10.1016/j.bmcl.2012.06.033 BindingDB Entry DOI: 10.7270/Q2BK1DHN
					More data for this Ligand-Target Pair