Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50396304'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50396304 (CHEMBL2172483) Show SMILES COc1ncccc1-c1ccc2nc(Nc3ccn[nH]3)c(-c3nc(C)nc(N)n3)n2c1 Show InChI InChI=1S/C20H18N10O/c1-11-24-17(28-20(21)25-11)16-18(26-14-7-9-23-29-14)27-15-6-5-12(10-30(15)16)13-4-3-8-22-19(13)31-2/h3-10H,1-2H3,(H2,23,26,29)(H2,21,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of mTOR by LanthaScreen assay				Bioorg Med Chem Lett 22: 4967-74 (2012) Article DOI: 10.1016/j.bmcl.2012.06.033 BindingDB Entry DOI: 10.7270/Q2BK1DHN
					More data for this Ligand-Target Pair