Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50396317'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50396317 (CHEMBL2172634) Show SMILES Cc1nc(Nc2cnn(c2)C2CCOC2)cc(n1)-c1c(Nc2ccn[nH]2)nc2cccnn12 Show InChI InChI=1S/C21H21N11O/c1-13-25-16(9-18(26-13)27-14-10-24-31(11-14)15-5-8-33-12-15)20-21(28-17-4-7-22-30-17)29-19-3-2-6-23-32(19)20/h2-4,6-7,9-11,15H,5,8,12H2,1H3,(H2,22,28,30)(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of mTOR by LanthaScreen assay				Bioorg Med Chem Lett 22: 4967-74 (2012) Article DOI: 10.1016/j.bmcl.2012.06.033 BindingDB Entry DOI: 10.7270/Q2BK1DHN
					More data for this Ligand-Target Pair