Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50499378'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50499378 (CHEMBL3734962) Show SMILES COc1ccc(cn1)-c1ccc2ncc(C(N)=O)c(Nc3ccc(cc3)C(C)(C)C#N)c2c1 Show InChI InChI=1S/C26H23N5O2/c1-26(2,15-27)18-6-8-19(9-7-18)31-24-20-12-16(17-5-11-23(33-3)30-13-17)4-10-22(20)29-14-21(24)25(28)32/h4-14H,1-3H3,(H2,28,32)(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	674	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr by lance ultra assay				Bioorg Med Chem 23: 7585-96 (2015) Article DOI: 10.1016/j.bmc.2015.11.003 BindingDB Entry DOI: 10.7270/Q2HD7ZPM
					More data for this Ligand-Target Pair