Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM151967'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM151967 (US8987457, 161) Show SMILES C[C@H]1CN(C[C@@H](N)[C@H]1n1ccnn1)c1ccncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cc(C)cc1F |r,wU:1.0,5.5,7.8,(-.67,1.9,;-2,1.13,;-2,-.41,;-3.33,-1.18,;-4.67,-.41,;-4.67,1.13,;-6,1.9,;-3.33,1.9,;-3.33,3.44,;-4.58,4.34,;-4.1,5.8,;-2.56,5.8,;-2.09,4.34,;-3.33,-2.72,;-4.67,-3.49,;-4.67,-5.03,;-3.33,-5.8,;-2,-5.03,;-2,-3.49,;-.67,-2.72,;.67,-3.49,;.67,-5.03,;2,-2.72,;3.33,-3.49,;4.67,-2.72,;4.67,-1.18,;6,-.41,;3.33,-.41,;2,-1.18,;3.33,1.13,;2,1.9,;.67,1.13,;2,3.44,;3.33,4.21,;3.33,5.75,;4.67,3.44,;4.67,1.9,;6,1.13,)| Show InChI InChI=1S/C26H25F3N8O/c1-14-9-17(28)23(18(29)10-14)24-16(27)3-4-20(33-24)26(38)34-21-11-31-6-5-22(21)36-12-15(2)25(19(30)13-36)37-8-7-32-35-37/h3-11,15,19,25H,12-13,30H2,1-2H3,(H,34,38)/t15-,19+,25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...				US Patent US8987457 (2015) BindingDB Entry DOI: 10.7270/Q2765D2M
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