Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM161986'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM161986 (US9682991, 35) Show SMILES CN([C@H]1CC[C@H](O)CC1)c1nn2c(nnc2c2OCCN(C)c12)-c1cccc(OC(F)(F)F)c1 |r,wU:2.1,wD:5.5,(-6.57,1.15,;-5.24,.38,;-5.24,-1.16,;-3.91,-1.93,;-3.91,-3.47,;-5.24,-4.23,;-5.24,-5.77,;-6.57,-3.47,;-6.57,-1.93,;-3.91,1.15,;-2.57,.39,;-1.24,1.15,;.23,.68,;1.13,1.92,;.23,3.17,;-1.24,2.69,;-2.57,3.46,;-2.57,5,;-3.91,5.77,;-5.24,5,;-5.24,3.46,;-6.57,2.69,;-3.91,2.69,;.62,-.81,;-.46,-1.9,;-.07,-3.38,;1.42,-3.78,;2.51,-2.69,;4,-3.09,;5.09,-2,;6.57,-2.4,;4.69,-.52,;5.49,-3.49,;2.11,-1.21,)| Show InChI InChI=1S/C22H25F3N6O3/c1-29-10-11-33-18-17(29)20(30(2)14-6-8-15(32)9-7-14)28-31-19(26-27-21(18)31)13-4-3-5-16(12-13)34-22(23,24)25/h3-5,12,14-15,32H,6-11H2,1-2H3/t14-,15-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III US Patent					Assay Description The biochemical assay to measure PIM-1 activity relies on the ADP Hunter assay kit (DiscoveRx Corp., Cat. #90-0077), that determines the amount of AD...				US Patent US9682991 (2017) BindingDB Entry DOI: 10.7270/Q2513WCB
					More data for this Ligand-Target Pair