Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM192553'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM192553 (US9187486, 15) Show SMILES N[C@H]1CCCN(C1)c1ccncc1Nc1ncc2ccc(nn12)-c1ccccc1F |r| Show InChI InChI=1S/C22H22FN7/c23-18-6-2-1-5-17(18)19-8-7-16-12-26-22(30(16)28-19)27-20-13-25-10-9-21(20)29-11-3-4-15(24)14-29/h1-2,5-10,12-13,15H,3-4,11,14,24H2,(H,26,27)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9187486 (2015) BindingDB Entry DOI: 10.7270/Q24748NM
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM192553 (US9187486, 15) Show SMILES N[C@H]1CCCN(C1)c1ccncc1Nc1ncc2ccc(nn12)-c1ccccc1F |r| Show InChI InChI=1S/C22H22FN7/c23-18-6-2-1-5-17(18)19-8-7-16-12-26-22(30(16)28-19)27-20-13-25-10-9-21(20)29-11-3-4-15(24)14-29/h1-2,5-10,12-13,15H,3-4,11,14,24H2,(H,26,27)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant Pim1 (unknown origin) by electrochemiluminescence assay				Bioorg Med Chem Lett 26: 5580-5590 (2016) Article DOI: 10.1016/j.bmcl.2016.09.067 BindingDB Entry DOI: 10.7270/Q261128M
					More data for this Ligand-Target Pair