Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM238545'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238545 (US9394297, 191) Show SMILES CCCNc1nc2c(cccc2nc1C)-c1cc2c(CCNC2=O)[nH]1 Show InChI InChI=1S/C19H21N5O/c1-3-8-20-18-11(2)22-15-6-4-5-12(17(15)24-18)16-10-13-14(23-16)7-9-21-19(13)25/h4-6,10,23H,3,7-9H2,1-2H3,(H,20,24)(H,21,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human full-length Pim1 expressed in Escherichia coli assessed as phosphorylation of biotinylated BAD peptide at Ser-112 preincubated fo...				ACS Med Chem Lett 7: 408-12 (2016) Article DOI: 10.1021/acsmedchemlett.5b00403 BindingDB Entry DOI: 10.7270/Q2MG7RD5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM238545 (US9394297, 191) Show SMILES CCCNc1nc2c(cccc2nc1C)-c1cc2c(CCNC2=O)[nH]1 Show InChI InChI=1S/C19H21N5O/c1-3-8-20-18-11(2)22-15-6-4-5-12(17(15)24-18)16-10-13-14(23-16)7-9-21-19(13)25/h4-6,10,23H,3,7-9H2,1-2H3,(H,20,24)(H,21,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.30	n/a	n/a	n/a	n/a	7.0	22
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9394297 (2016) BindingDB Entry DOI: 10.7270/Q2G44P78
					More data for this Ligand-Target Pair