Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM248924'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM248924 (US9434725, 155) Show SMILES N#CCn1cc(cn1)-c1cc2n(ncc2cn1)-c1cccc(n1)N1CCCNCC1 Show InChI InChI=1S/C21H21N9/c22-5-9-29-15-17(14-25-29)18-11-19-16(12-24-18)13-26-30(19)21-4-1-3-20(27-21)28-8-2-6-23-7-10-28/h1,3-4,11-15,23H,2,6-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.144	-56.2	n/a	n/a	n/a	n/a	n/a	7.2	25
F. HOFFMANN-LA ROCHE AG US Patent					Assay Description PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...				US Patent US9434725 (2016) BindingDB Entry DOI: 10.7270/Q2CF9P1N
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Mus musculus (Mouse))	BDBM248924 (US9434725, 155) Show SMILES N#CCn1cc(cn1)-c1cc2n(ncc2cn1)-c1cccc(n1)N1CCCNCC1 Show InChI InChI=1S/C21H21N9/c22-5-9-29-15-17(14-25-29)18-11-19-16(12-24-18)13-26-30(19)21-4-1-3-20(27-21)28-8-2-6-23-7-10-28/h1,3-4,11-15,23H,2,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	518	n/a	n/a	n/a	n/a	n/a	n/a
F. HOFFMANN-LA ROCHE AG US Patent					Assay Description BaF3, a murine interleukin-3 dependent pro-B cell line, parental cells, BaF3 PIM1 cells, BaF3 PIM2 cells, and MM1.S (multiple myeloma) cells were see...				US Patent US9434725 (2016) BindingDB Entry DOI: 10.7270/Q2CF9P1N
					More data for this Ligand-Target Pair