Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM26677'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM26677 (4-(3-chlorophenyl)-6-(5-ethyl-2-hydroxyphenyl)-2-o...) Show SMILES CCc1ccc(O)c(c1)-c1cc(-c2cccc(Cl)c2)c(C#N)c(=O)[nH]1 Show InChI InChI=1S/C20H15ClN2O2/c1-2-12-6-7-19(24)16(8-12)18-10-15(17(11-22)20(25)23-18)13-4-3-5-14(21)9-13/h3-10,24H,2H2,1H3,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	7.5	23
Valeant Pharmaceuticals Research and Development					Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...				Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V
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