Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM291184'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291184 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES CC(C)c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C23H28N6O2/c1-13(2)15-8-19-17(26-9-15)4-5-18(27-19)23(31)28-20-10-25-7-6-21(20)29-11-14(3)22(30)16(24)12-29/h4-10,13-14,16,22,30H,11-12,24H2,1-3H3,(H,28,31)/t14-,16+,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291184 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES CC(C)c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C23H28N6O2/c1-13(2)15-8-19-17(26-9-15)4-5-18(27-19)23(31)28-20-10-25-7-6-21(20)29-11-14(3)22(30)16(24)12-29/h4-10,13-14,16,22,30H,11-12,24H2,1-3H3,(H,28,31)/t14-,16+,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				US Patent US9580418 (2017) BindingDB Entry DOI: 10.7270/Q2X92DB9
					More data for this Ligand-Target Pair