Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM291205'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291205 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES COC1CCN(CC1)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H34N6O2/c1-18-13-20(28)17-33(16-18)26-7-10-29-15-25(26)31-27(34)23-6-4-19-3-5-21(14-24(19)30-23)32-11-8-22(35-2)9-12-32/h3-7,10,14-15,18,20,22H,8-9,11-13,16-17,28H2,1-2H3,(H,31,34)/t18-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291205 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES COC1CCN(CC1)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H34N6O2/c1-18-13-20(28)17-33(16-18)26-7-10-29-15-25(26)31-27(34)23-6-4-19-3-5-21(14-24(19)30-23)32-11-8-22(35-2)9-12-32/h3-7,10,14-15,18,20,22H,8-9,11-13,16-17,28H2,1-2H3,(H,31,34)/t18-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description Pim-1 and Pim-3 kinase assays-20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				US Patent US9580418 (2017) BindingDB Entry DOI: 10.7270/Q2X92DB9
					More data for this Ligand-Target Pair