Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM50131236'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50131236 (CHEMBL3634765 | US9260425, 401) Show SMILES C1CN(CCN1)c1cccc(n1)-c1n[nH]c2cnc(cc12)N1CCOCC1 Show InChI InChI=1S/C19H23N7O/c1-2-15(22-17(3-1)25-6-4-20-5-7-25)19-14-12-18(21-13-16(14)23-24-19)26-8-10-27-11-9-26/h1-3,12-13,20H,4-11H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	3.29	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Genetech, Inc. US Patent					Assay Description PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J....				US Patent US9260425 (2016) BindingDB Entry DOI: 10.7270/Q2RR1X3X
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50131236 (CHEMBL3634765 | US9260425, 401) Show SMILES C1CN(CCN1)c1cccc(n1)-c1n[nH]c2cnc(cc12)N1CCOCC1 Show InChI InChI=1S/C19H23N7O/c1-2-15(22-17(3-1)25-6-4-20-5-7-25)19-14-12-18(21-13-16(14)23-24-19)26-8-10-27-11-9-26/h1-3,12-13,20H,4-11H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of Pim1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins				Bioorg Med Chem Lett 25: 5258-64 (2015) Article DOI: 10.1016/j.bmcl.2015.09.052 BindingDB Entry DOI: 10.7270/Q2TT4SR7
					More data for this Ligand-Target Pair